Aiming at the technical problems of the irregular brick concrete structure building demolition by blasting and the lack of directional collapse space,a demolition method of in-situ collapse combined with directional toppling' was proposed based on a blasting demolition engineering practice of a 7-story ‘凹’ style brick-concrete structure building.By innovative design of blasting cut,hole network parameters and blasting network,an expected blasting demolition effect was achieved.Using ANSYS/LS-DYNA finite element analysis software,the process of building collapse was simulated and the scientific nature of the design scheme was verified.The results show that the middle part of the building touches the ground first,and the two sides of the building are collapsed piecewisely and inwardly.There is basically no recoiling phenomenon,and it can collapse according to the design scheme.The simulation results are basically consistent with the blasting results.In the corner on both sides and north-south and central area,the explosion pile overflowed the original site of the building,so it is necessary to pay attention to the collapse space margin at this location,and take effective safety protection measures.By the method of piecewise and inward collapse,the demolishing of the special-shaped brick-concrete structure building has achieved the purpose of reducing the collapse accumulation range of the building and improving the disintegration effect.