With the increase of depth,the ore bodiy in Wunugetushan Cu-Mo Mine has serious interpenetration,and the position of ore body line is not accurate,which leads to the mixed explosion of ore and rock,and increases the ore loss and dilution rate.Blasting parameters have great influence on ore loss and dilution in open-pit mining.According to the on-site blasting construction situation of the Wunugetushan Cu-Mo mine,the marker method was used to monitor the blasting displacement to select a reasonable initiation position.The delay time was determined by the blasting delay time experiment,and the blasting sequence was controlled to change the instantaneous free surface in the process of blasting.Four separate blasting tests of ore and rock were carried out,and a comparative statistical analysis of blasting toes rate and the power consumption of the coarse crushingwas carried out.The results show that the optimal blasting network design plan is 9 ms between holes,25 ms between rows,65 ms in the back row and 100 ms delayed interval at the separation boundary of ore and rock.The vertical distance between the top of the blasting pile on both sides of the ore and rock and the bottom of the boundary between the ore and rock is 2~3 m,which achieves the effective control of the movement direction of rock and realizes the purpose of the separation of ore and rock.The research results are of great significance for optimizing blasting parameters,reducing crushing costs,and reducing ore loss and dilution.