In order to simultaneously improve the high-temperature wear and oxidation resistance of Ti6Al4V alloy, the composite coatings are prepared on the surface of Ti6Al4V alloy by laser cladding with the precursor mixed NiCr/Cr3C2- Al- Si powder. Microstructure, wear and high temperature oxidation resistance of laser cladding coatings are analyzed. The results show that TiC, Ti5Si3 and Cr3Si particulate reinforced γ - Ni/Al8Cr5 matrix composite coatings are formed. The average micro- hardness of the composite coating is 750 HV0.5, and is almost twice as much as that of Ti6Al4V alloy. At room temperature, compared to Ti6Al4V alloy, the composite coating exhibits excellent tribological property due to its high hardness. While at high temperature of 600 ℃ , the formation of protective transferred layers between the sliding surface of Ti6Al4V alloy and the ceramic couple can play a positive self-lubrication role. Compared with the Ti6Al4V alloy, the wear resistance of the composite coating has slight decrease because of the formation of micro-cracks on the worn surface at high temperature. After isothermal oxidation tests at 800 ℃ for 32 h, the Ti6Al4V alloy is oxidized quickly because of the high affinity of Ti towards O and the non- protective oxide scales of TiO2. The composite coating can form continuous Al2O3, NiO and Cr2O3 oxide scales on the surface, which is more protective than TiO2. The high- temperature oxidation resistance of the laser cladding composite coating is approximately 8.4 times higher than that of the Ti6Al4V alloy.