The combination of wavelength dispersive and energy dispersion X-ray fluorescence analysis would take both of advantage of wavelength dispersive and energy dispersive. Now, A combined wavelength dispersive and energy dispersion X-ray fluorescence spectrometer was used in analysis of major, minor and trace elements in the soil samples taken from the fields around a Pb-Zn mine. The WD-ED XRF analytical method performance was evaluated by their uncertainty. The results revealed that (1) WDXRF shows more sensitive to the light elements, such as Na, Mg, Al, Si. (2) The limits of detections (LOD) of Na2O, MgO, Al2O3, P2O5, K2O by WDXRF are lower than those by EDXRF. The LODs of of SiO2, SO3, CaO, MnO and Fe2O3 are lower than those by WDXRF. For the minor and trace elements which have heavy overlap of spectral lines, WDXRF gives lower LOD; (3) For major elements, the analytical accuracy of the elements before K by WDXRF are better than those by EDXRF. For the elements after Ca, the accuracy by EDXRF are better. For minor and trace elements, if there are heavy overlapped spectral lines, WDXRF give more accurate results. Without heavy overlapped spectral lines, the accuracy of EDXRF is better; (4) Powder pellets with wax as binder were used in WD-EDXRF analysis without any observed drop of sample powder. Soil samples were determined. Generally, no significant differences were observed between measured results and certified values. (5) The WD-EDXRF method was applied to the determination of major, minor and trace elements in the surface soils in the mining area, and high concentrations of Cu, Pb and Zn were detectable; (6) The distributions of heavy elements were obtained in soils from the agricultural fields, and the high concentrations of Pb observed, which implies that the agricultural soils may have been polluted by the mining activities. And health risks need to be evaluated further.