Inspirable nano-particles into lungs in the atmosphere were studied in this paper. Field emission scanning electron microscope (FSEM) and X-ray energy dispersive spectrometer were used to investigate the morphology and major constituents of inspirable nano-particles into lungs systematically. The results showed that most of the inspirable nano-particles in the atmosphere are spherical and ellipsoidal, with smooth surface and dense structure. The smaller nano-particles are clustered into loose floccule, with the sizes in the range of 30 to 100 nm. The constant elements in the nano-particles are close consistent with the large particle pollutants, which mainly contain C, O, A1, Si, Na, Mg, K, Ca, Fe, S and Cl etc. The point Analysis of EDS confirmed that the element content of Cl and S in some nano-particles is significantly increased, while others mainly contain C and O. It is believed that the surface of nano inorganic dust particles was adsorbed by the organic pollutants to form the core-shell structure nano-particles pollutants in the process of aerosol formation. Thus, reducing anthropogenic emissions of organic pollutants has great influence on the formation of inspirable nano-particles.