Installation errors of a stabilized platform with a frame structure affect the calculation accuracy of the line-of-sight (LOS) angular velocity. Mathematical descriptions for the axis system deviation of frames are given. Based on these, calculation methods for a three degree- of-freedom infrared stabilized platform are studied under the conditions of axis system deviation and cross coupling of sensitive axes of gyros. The influences on the measuring accuracy of LOS angular velocity caused by these two kinds of installation errors are compared. It is shown by simulation results that compensating for installation errors can effectively improve the measuring accuracy of LOS angular velocity. The results are important for error index decomposition for the design of a late-model-stabilized platform with a frame structure.