In recent years, Chinese researchers have done a lot of representative work in rational design, preparation, functional modification, exploration of physicochemical mechanisms, and biomedical application of biomaterial-based biosensor technologies. To showcase the latest research achievements of Chinese scientists in the field of biomedical detection and stimulate the wide interest of all sectors of society in biomaterials and novel sensing technologies, the editorial office of Journal of Inorganic Materials invited me as the Guest Editor to organize a topical section on the theme of "Anti-epidemic biomaterials". This topical section contains the latest review articles and research papers related to the detection and diagnosis of viruses, bacteria and cancer cells, involving new biosensor technologies for COVID-19 (electrochemical sensor, SERS biosensor, SPR biosensor, etc.), fluorescence detection technology, anti-bacterial nano-enzyme technology, etc. It is hoped that this topical section will promote the cooperation of researchers and scientists from various fields with different disciplinary backgrounds, and jointly promote the innovation and development of the field of biomedical detection, with a view to changing and optimizing the diagnosis and treatment of various diseases in clinical medicine so as to better benefit human health.